Expression of genome defence protein members in proliferating and quiescent rat male germ cells and the Nuage dynamics.
During epigenetic reprogramming germ cells activate alternative mechanisms to maintain the repression retrotransposons.This mechanism involves the recruitment of genome defence proteins such as MAEL, PIWIL4 and TDRD9, which associate with piRNAs and promote Line-1 silencing.MAEL, PIWIL4 and TDRD9 form the piP-bodies, which organization and dynamics